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Rotary motion of DNA rotors on nanopores. Top row: Uncooked video with the Cy5 channel of every rotor. Center row: corresponding solitary-particle localization results of equally ends with the DNA rotors. The place of the current frame is marked as orange and blue dots, along with the trajectory of the 10 frames prior to The existing frame is demonstrated as strong strains.

Human Rad51 filaments on double- and solitary-stranded DNA: correlating common and irregular forms with recombination operate.

Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins

Considering that 2000, Dekker has shifted the leading aim of his work toward biophysics where by he reports the Houses of one biomolecules and cells using the tools of nanotechnology. This change of subject was driven by his fascination with the outstanding operating of biological molecular structures, in addition to with the long-expression standpoint that a lot of exciting discoveries is often envisioned in this area.[5] Existing traces of exploration in his biophysics team are during the parts of:[six]

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Experimental stage diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,

You're a Christian. If you can make this kind of synthetic mobile, would you be one particular step nearer to God, or would the function of God have diminished to some degree all over again?

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Comprehending basic processes regulating the spatial and dynamic organisation from the DNA in Reside cells.

‘The fantastically subtle way in which features in mother nature operate by no means ceases to amaze me. If we solve the puzzle of how everyday living arrived into staying, I assume that my amazement in the complexity of generation will likely have enhanced and with it my awe for your greatness of your Creator.’

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2001, discovery of one-electron transistors at home temperature dependant on nanotubes; realization of first logic circuits with carbon nanotube devices; and discovery of the molecular structure of DNA restore enzymes with AFM

Visualization of unstained DNA nanostructures with State-of-the-art in-aim transmission electron microscopy techniques

Stable-condition nanopores have demonstrated being a amazingly functional probe for one-molecule Investigation of DNA. I'll describe a few of our current findings – particularly DNA knots – in addition to our efforts to expand the abilities of stable-condition nanopores even even more, while in ceesdekker.net the route of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.